Since I started in 1982, I am somewhat old school I use tape drives. I currently have an HP LTO 3 and two VXA-320 backup drives on SCSI. I prefer tape drives because hard drives fail.
I setup Samba shares to backup the /var/www files to one set of tapes. I have VEEAM 9.5 to backup the VMs on my HP DL360e Gen8 server to my workstation’s eSata drive. I use Symantec Backup Exec 2010 to back that directory with the current VM backups to another set of tapes. I keep the previous VM backups in another eSata directory. I rotate 3 sets of tapes for my backups. I keep the wp-config.php files on my workstation because they are flagged 700 so the backup software can’t read them. VEEAM does work with tape drives directly. I am considering a LTO-5 tape drive for my workstation for VEEAM to use.